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Adequate GSH maintains GPX4 in its reduced state, preventing oxidative inactivation, whereas GSH depletion leads to decreased GPX4 activity or even complete inactivation

One of its most unique features is its half-life and duration

Notably, the mechanism by which metal NPs exert their antimicrobial effect is vastly different from those of antibiotics, and concerns regarding drug resistance in gut microbiota are minimized

As a result, the launch has arrived later than originally expected

Discontinuation rates in everyday settings are also higher than whats reported in clinical trials, highlighting the importance of a more tailored approach